Daniel A. Harrington will be my mentor this summer. We talked about what is going on in the lab and what my part might be. In this lab they are studying a protein called perlecan. It is a protein that borders the cells of the prostate, and is seen to be degraded as prostate cancer metastasizes. The lab wants to study this protein and the effects that cancer cells may have on it. In order to do so they need to perform experiments on cells bonded to domains of perlecan. To do this the perlecan domains need to be covalently bonded to a dish in a monolayer. This is where I come in. To do this sounds simple but it is a delicate procedure. The goal is to make it an easy process that anyone in the lab can use these dishes for experiments.
Sounds like there may be lots of chemistry here. Please share info once you have finished your program.
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